Weill Cornell Medicine · New York

Computational genomics & AI for Medicine

We build multimodal artificial intelligence and computational genomics methods that turn biomedical data — images, sequences, and clinical signals — into discoveries and tools that reach patients.

Iman Hajirasouliha, Ph.D. Principal Investigator · Associate Professor · Co-Director, Tri-I CBM
Research

From data to the clinic, across modalities.

Our work spans multimodal AI, genomics, and precision medicine — with a throughline of building methods rigorous enough for biology and reliable enough for care.

1

Foundation Models for IVF & Embryology

Foundational AI trained on millions of time-lapse images for embryo selection, automated blastocyst ploidy prediction, and validation of clinical efficacy.

2

Metagenomics & Microbiome

Leading the NIH-funded Microbiome In A Bottle (MIAB) project. Modular metagenomic analysis systems (CAMP) and novel algorithms for microbial genomics, in collaboration with the international MetaSUB Consortium.

3

Multimodal & Clinical AI

Deep learning that fuses pathology, radiology, and imaging — building models designed for real diagnostic and decision-support settings.

4

Structural Variation & Genome Assembly

Algorithms and deep-learning frameworks for structural variant discovery and assembly.

5

Cancer & Precision Oncology

Weakly-supervised tumor-purity prediction from H&E slides, prostate-cancer foundation models, and inference of lineage plasticity in metastatic disease.

6

Women's Health

AI for the automated detection of polycystic ovary syndrome and ovarian morphology on ultrasonography, and downstream reproductive-health applications.

The Principal Investigator

Iman Hajirasouliha

Associate Professor of Systems and Computational Biomedicine at Weill Cornell Medicine, Cornell University, and Co-Director of the Tri-Institutional Computational Biology & Medicine Ph.D. program (Weill Cornell, Memorial Sloan Kettering, and The Rockefeller University).

His research develops multimodal AI and computational methods across genomics, clinical imaging, and precision medicine. He is a member of the Englander Institute for Precision Medicine and the Meyer Cancer Center. He earned his Ph.D. in Computing Science at Simon Fraser University, with postdoctoral research at Brown University and Stanford University, and a fellowship at the Simons Institute, UC Berkeley.

Selected Publications

Recent work.

A selection of recent peer-reviewed papers.

People

The team.

The researchers behind the lab, across the Tri-Institutional and Cornell programs.

Iman Hajirasouliha
Iman Hajirasouliha, Ph.D.
Principal Investigator · Associate Professor · Co-Director, Tri-I CBM
Lieke Michielsen
Lieke Michielsen
Postdoc · joint with Tilgner Lab
Suraj Rajendran
Suraj Rajendran
Ph.D. · Tri-I CBM · NSF GRF · joint with Wang Lab
William Phu
William Phu
Ph.D. Candidate· Tri-I CBM
Eeshaan Rehani
Eeshaan Rehani
Ph.D. Candidate · BME, Cornell
Shenni Liang
Shenni Liang
Ph.D. Candidate · Tri-I CBM
Pavan Narahari
Pavan Narahari
Part-time Bioinformatics Scientist · Former M.Sc. & incoming Ph.D., Tri-I CBM
Lauren Mak
Lauren Mak
Research Specialist · Former Ph.D. student, Tri-I CBM
Hriday Bhambhvani
Hriday Bhambhvani
Urology Resident · PGY-4
Tabassum Fabiha
Tabassum Fabiha
Rotation student · Ph.D., Tri-I CBM
Romer Miranda
Romer Miranda
Summer Student · Computational Biology

Where alumni have gone

Dr. Camir Ricketts → Bioinformatics Scientist - AI, NVIDIA · Dr. David Danko → CTO, Biotia · Dr. Dmitrii Meleshko → Faculty, ITMO University · Dr. Matthew Brendel → Senior Consultant, ClearView Healthcare Partners · Dr. Josue Barnes → AI Success and Strategy Lead, Arya Health · Dr. Hamid Mohamadi → Senior Applied Scientist, Amazon · Dr. Pegah Khosravi → Associate Professor, University of Central Florida (UCF) Institute for Artificial Intelligence · Dr. Wei Wei → Postdoc, MSKCC.

Opportunities

Join the lab.

We welcome curious researchers who want to work at the intersection of computational genomics, machine learning, and medicine — from quantitative, biological, and clinical backgrounds alike.

1

Graduate Students

Already admitted to one of our affiliated programs — the Tri-Institutional CBM program, the Weill Cornell Graduate School, Cornell Ithaca, Cornell Tech, and others? Email Dr. Hajirasouliha directly. Prospective students should apply to the relevant program first and mention the lab in their application.

2 · We're hiring

Postdoctoral Associate — AI for Reproductive Medicine

We're using AI to change how reproductive medicine is practiced, and looking for a postdoc to help lead the next chapter.

Postdoctoral Associate AI for Reproductive Medicine New York City Rolling review · Priority by July 31, 2026
The role

We are recruiting a Postdoctoral Associate in AI for Reproductive Medicine to develop the next generation of our AI models: large-scale foundation models, multimodal learning, and clinically deployable tools that can improve outcomes for patients. Our research has already produced patented technologies, and you'll have the opportunity to help translate new models into deployable products, with exposure to IP and entrepreneurship along the way.

Who you are

You'd be a great fit if you have (or are about to complete) a Ph.D. in machine learning, computer science, computational biology, biomedical engineering, or a related field, with strong deep-learning and generative-AI skills. I'm especially keen to hire someone who can build product- and clinical-grade systems: robust, well-engineered, validated models and software that move beyond prototypes into real clinical and product settings. Strong software engineering and experience with model deployment/MLOps, medical imaging, foundation models, or clinical/regulatory translation (e.g., software as a medical device) are valued; a passion for translational, patient-facing impact is essential. Exceptional candidates without a Ph.D. but with equivalent research and/or industry experience will also be considered for a comparable Staff or Research Associate position.

What we offer

A highly collaborative home across the Tri-Institutional community (Weill Cornell, Memorial Sloan Kettering, Rockefeller), direct access to world-class clinical collaborators and data, strong mentorship, and the chance to publish in top venues and ship tools that reach the clinic — all in the heart of New York City.

How to apply

Applications are reviewed on a rolling basis, and the position is open until filled, with priority given to applications received by July 31. Interested, or know someone who is? Email Dr. Hajirasouliha with your CV and a short note on what draws you to this work.

Apply / get in touch

3

Postdocs

Beyond the call above, prospective postdoctoral applicants interested in computational genomics, metagenomics and the microbiome, or general AI in medicine are welcome to email Dr. Hajirasouliha directly with a CV and a brief note of interest.

4

MD, MD/PhD & Residents

MD and MD/PhD students, and Weill Cornell residents in their dedicated research years, are encouraged to reach out about research projects in the lab.

In the news

Press & coverage.

Support

Funding.

Research in the lab is supported by federal and foundation funding.

Current
NIH / NIGMS — MIRA (2R35GM138152-06; PI) NIH / NHGRI (R01HG012467; PI Subaward) NIH / NICHD (R21HD116139-01; MPI) NIH / NCI (U24 CA264032-01; Co-PI) NIH / NIGMS — T32 (2T32GM132083-06; Co-PI) Hirschl–Weill–Caulier Trust (PI) Prostate Cancer Foundation — PCF Challenge Award (Co-PI) WCM Start-up Funds (PI)
Past
NIH / NIGMS (R35GM138152-01; PI) Renewed → current Cornell CALS Moonshot Seed Grant (Co-PI) Mae Stone Goode Grant Award (MPI) Horizon 2020 — PANGAIA (EU 872539; Collaborator) H2020-MSCA-ITN — ALPACA (EU 956229; Collaborator) Starr Cancer Consortium (I15-0027; PI) NSF (Award 1840275; PI) Cornell University Multi-Investigator Seed Grant (PI) NVIDIA GPU Grant (PI) Google Cloud Platform Research Credits (PI) XSEDE Research Allocations (PI) Empire AI Alpha GPU Allocations (PI)